What Is LSD? — History, Pharmacology, and Safety Guide

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Complete LSD guide for the DMV. Lysergic acid diethylamide (LSD) was first synthesized by Albert Hofmann in 1938. It acts primarily on serotonin 5-HT2A receptors, producing 8 to 12 hour experiences. Comparison to psilocybin, microdosing research, cross-tolerance, reagent testing with Ehrlich, and harm reduction for responsible use.