Question 1

What is ibogaine?

Accepted Answer

Ibogaine is a naturally occurring psychoactive alkaloid found in the root bark of Tabernanthe iboga, a shrub native to Central West Africa. It produces an extended experience and has attracted scientific attention in addiction research. Ibogaine remains a Schedule I controlled substance under federal law.

Question 2

Can ibogaine treat opioid addiction?

Accepted Answer

Multiple observational studies report that ibogaine significantly reduces opioid withdrawal symptoms within 12–24 hours and provides sustained craving reduction lasting weeks to months after a single treatment. Its metabolite noribogaine has a long half-life and is believed responsible for lasting anti-craving effects. Clinical trials are underway globally, and Arizona earmarked $5 million for ibogaine research in its FY2026 budget.

Question 3

Is ibogaine safe?

Accepted Answer

Ibogaine carries serious medical risks that distinguish it from other psychedelics. It affects the heart's QT interval and has been associated with fatalities due to cardiac arrhythmia. A thorough cardiac evaluation (EKG) is essential before use. It should never be taken without medical supervision, cardiac monitoring, and a drug-free washout period. Dangerous interactions exist with opioids, methadone, SSRIs, and antipsychotics.

Question 4

Is ibogaine legal in Washington DC?

Accepted Answer

Initiative 81 makes certain non-commercial activities involving specified entheogenic plants and fungi among MPD's lowest enforcement priorities. It does not legalize ibogaine or override federal law; ibogaine remains a Schedule I controlled substance federally.