Question 1

What is ibogaine?

Accepted Answer

Ibogaine is a naturally occurring psychoactive alkaloid found in the root bark of Tabernanthe iboga, a shrub native to Central West Africa. It produces a unique extended experience lasting 24–36 hours and has attracted significant scientific attention for its ability to interrupt opioid addiction by reducing withdrawal symptoms and cravings. Ibogaine is covered under DC's Initiative 81.

Question 2

Can ibogaine treat opioid addiction?

Accepted Answer

Multiple observational studies report that ibogaine significantly reduces opioid withdrawal symptoms within 12–24 hours and provides sustained craving reduction lasting weeks to months after a single treatment. Its metabolite noribogaine has a long half-life and is believed responsible for lasting anti-craving effects. Clinical trials are underway globally, and Arizona earmarked $5 million for ibogaine research in its FY2026 budget.

Question 3

Is ibogaine safe?

Accepted Answer

Ibogaine carries serious medical risks that distinguish it from other psychedelics. It affects the heart's QT interval and has been associated with fatalities due to cardiac arrhythmia. A thorough cardiac evaluation (EKG) is essential before use. It should never be taken without medical supervision, cardiac monitoring, and a drug-free washout period. Dangerous interactions exist with opioids, methadone, SSRIs, and antipsychotics.

Question 4

Is ibogaine legal in Washington DC?

Accepted Answer

Ibogaine is covered under Washington DC's Initiative 81, passed in November 2020, which makes the investigation and arrest of adults for entheogenic plants and fungi among the lowest law enforcement priorities. At the federal level, ibogaine remains a Schedule I controlled substance. Colorado also decriminalized ibogaine under Proposition 122 in 2022.